• Theodore as Ed
  • Simon as Edd/Double D
  • Alvin as Eddy
  • Jeanette as Nazz (both girlfriends to Simon and Double D)
  • The Wolf (from Tex Avery cartoons) as Kevin
  • Kitten (from Teen Titans) as Sarah
  • Edmond (from Rock-a-Doodle) as Jimmy
  • Hiro Hamada (from Big Hero 6) as Rolf
  • Piglet (from Winnie the Pooh) as Johnny
  • Cri-kee (from Mulan) as Plank
  • Brittany as Lee Kanker
  • Gogo Tomago (from Big Hero 6) as Marie Kanker
  • Eleanor as May Kanker
  • Ian Hawke as Eddy's Brother

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