- Jeanette as Blossom (both are bookworms)
- Simon as Brick (both are smart)
- Eleanor as Bubbles (both have pigtails)
- Theodore as Boomer (both are cute)
- Brittany as Buttercup (both are tomboys)
- Alvin as Butch (both are mischievous)
- Dave as Professor Utonium
- Vinny as Ms. Keane
- Ian Hawke as Mojo Jojo
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