- Wakko Warner as E.B.
- Yakko Warner as Easter Bunny
- Dr. Otto Scratchansniff as Fred O'Hare
- Hello Nurse as Sam O'Hare
- Mr. Ka-Boom as Henry O'Hare
- Mrs. Ka-Boom as Bonnie O'Hare
- Mindy as Alex O'Hare
- Dot Warner as Fluffy
- Slappy Squirrel as Patch
- Rita as Bit
- Katie Ka-Boom as Mrs. Beck
- Ralph the Guard as David Hasselhoff
- Brain as Carlos
- Pinky as Phil
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