- Caesar as Kermit the Frog
- General Aldo as Fozzie Bear
- Lisa as Annie Sue Pig
- Governor Kolp as Robin the Frog
- Mandemus as Sweetums
- Virgil as Scooter
- MacDonald as Gonzo the Great
- Abe the Teacher as Uncle Deadly
- Mutant Captain as Dr. Bunsen Honeydew
- Alma as Miss Piggy
- Mendez as Beaker
- Doctor as Janice
- and more
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