- Commander Alex Hopper as Kermit the Frog
- Commander Stone Hopper as Fozzie Bear
- Cora Raikes as Miss Piggy
- Samantha "Sam" Shane as Janice
- Captain Nagata as Gonzo the Great
- Cal Zapata as Rizzo the Rat
- Admiral Terrance Shane as Uncle Deadly
- The U.S. Secretary of Defense as Bobo the Bear
- Walter "Beast" Lynch as Dr. Bunsen Honeydew
- Lieutenant Colonel Mick Canales as Beaker
- Dr. Nogrady as Crazy Harry
- Jimmy "Ordy" Ord as Dr. Teeth
- Chief Engineer Hiroki as Animal
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