Berman
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[edit] In Memory
[edit] Patient Information
Age: 34
Sex: Male
Diagnosed: 2/98
Location: Medford, Oregon
Diagnosis: Stage IV DSRCT. Nine-inch diameter primary tumor in the pelvic cul de sac, and numerous thoracic metastatic tumors. First diagnosed as carcinoma of unknown origin.
Hospital: Fred Hutchinson Cancer Research Center
- Consultation: Children's Hospital in Seattle
- Consultation: Memorial Sloan Kettering Cancer Center
- Second Opinion: MD Anderson Cancer Center Houston, TX
- Surgery: University of Washington Medical Center
- Oncologist
No evidence of disease: 7/4/99
Passed Away: 9/29/00
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[edit] Treatment
Chemotherapy
- First line -bleomycin, etoposide, cisplatinum
- Altered (Sloan Kettering) P6 protocol - VACIME - vincristine, Adriamycin, Cytoxan, Ifosfamide, mesna and etoposide, at very high doses.
Surgery
- Removed the entire tumor and found clean margins on all sides except bladder, which showed microscopic infiltration. Based on prior instructions, they did not resect the bladder.
Autologous stem cell transplant
- High dose chemo: Busulphan, thiotepa, and melphalan.
Radiation
- Six week course of localized radiation at original site of primary tumor.
[edit] Time Line
| Date | Test | Treatment | Chemicals | Result |
|---|---|---|---|---|
| 2/98 | 0 | 0 | 0 | Found nine-inch diameter primary tumor in the pelvic cul de sac, and numerous thoracic metastatic tumors. |
| 3/98 | 0 | Chemotherapy 1 - high dose | BEP =bleomycin, etoposide, cisplatinum | 0 |
| 4/98 | 0 | Chemotherapy 2 - high dose | BEP =bleomycin, etoposide, cisplatinum | 0 |
| 5/98 | 0 | Chemotherapy 3 - high dose | VACIME =vincristine, Adriamycin, Cytoxan, Ifosfamide, mesna and etoposide | 0 |
| 6/98 | 0 | Chemotherapy 4 - high dose | VACIME = vincristine, Adriamycin, Cytoxan, Ifosfamide, mesna and etoposide | 0 |
| 7/98 | 0 | Chemotherapy 5 - high dose | VACIME =vincristine, Adriamycin, Cytoxan, Ifosfamide, mesna and etoposide | 0 |
| 8/98 | 0 | Chemotherapy 6 - high dose | VACIME =vincristine, Adriamycin, Cytoxan, Ifosfamide, mesna and etoposide | 0 |
| 9/98 | 0 | Surgery | 0 | Removed the entire tumor and found clean margins on all sides except bladder, which showed microscopic infiltration. Based on prior instructions, they did not resect the bladder. |
| 10/98 | 0 | 0 | 0 | 0 |
| 11/98 | 0 | Autologous Stem Cell Transplant - high dose chemotherapy | Busulphan, thiotepa, and melphalan | 0 |
| 12/98 | 0 | 0 | 0 | 0 |
| 1/99 | 0 | 0 | 0 | 0 |
| 2/99 | 0 | Radiation six-week course | Localized radiation at the original site of the primary tumor | 0 |
| 3/99 | 0 | Radiation six-week course | Localized radiation at the original site of the primary tumor | 0 |
| 4/99 | 0 | 0 | 0 | 0 |
| 5/99 | 0 | 0 | 0 | 0 |
| 6/99 | 0 | 0 | 0 | 0 |
| 7/4/99 | 0 | 0 | 0 | No evidence of disease. |
| 8/99 | 0 | 0 | 0 | 0 |
| 9/99 | 0 | 0 | 0 | 0 |
| 10/99 | 0 | 0 | 0 | 0 |
| 11/99 | 0 | 0 | 0 | 0 |
| 12/99 | 0 | 0 | 0 | 0 |
| 1/00 | 0 | 0 | 0 | 0 |
| 2/00 | 0 | 0 | 0 | 0 |
| 3/00 | 0 | 0 | 0 | 0 |
| 4/00 | 0 | 0 | 0 | 0 |
| 5/00 | 0 | 0 | 0 | 0 |
| 6/00 | 0 | 0 | 0 | 0 |
| 7/00 | 0 | 0 | 0 | 0 |
| 8/00 | 0 | 0 | 0 | 0 |
| 9/29/00 | 0 | 0 | 0 | Passed Away |
22
- Time line approximate based on statements
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