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Bidleman

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In Memory

SmsunflShawn


Patient Information

Age: 30

Sex: Female

Diagnosed: 11/02

Location: Michigan

Diagnosis: Stage IV DSRCT. Large liver tumors.

Hospital: University of Michigan Comprehensive Cancer Center

Oncologist

No evidence of disease: 2/23/04

Relapse: 12/22/04

Current: Stable disease August 2006.

Passed away: 11/20/08

Caringbridge Journal

Shawn

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Treatment

Chemotherapy

Vincristine, Doxorubicin, Cyclophosphamide, Etoposide, Ifosfamide

Surgery

  1. Removed 60% of pancreas, 10% of stomach, a blood vessel, and 50 smaller tumors.
  2. Total hysterectomy, and to reroute drains. Now draining on the inside from pancreas to large intestine.
  3. Debulking -Removed one fist size tumor and five smaller ones.

Clinical Trial

Phase II - AP23573
Receives 12.5 mg daily for 5 days every other week. The side affects encountered are high sugar, edema, and high cholesterol.
Rapamycin Analog On orphan and fast track status for the treatment of soft-tissue and bone sarcomas. FDA approved.

Time Line

Date Test Treatment Chemicals Result
11/20/02 0 0 0 Large liver tumor appears
12/02/02 0 Surgery 0 Removed 60% of pancreas, 10% of stomach, a blood vessel, and 50 smaller tumors.
1/21/03 0 Surgery 0 Total hysterectomy, and to reroute drains. Now draining on the inside from pancreas to large intestine.
2/03 0 0 0 0
3/03 0 0 0 0
4/7/03 0 Chemotherapy 1 Vincristine, Doxorubicin, Cyclophosphamide, Etoposide, Ifosfamide 0
5/28/03 0 Chemotherapy 2 Vincristine, Doxorubicin, Cyclophosphamide, Etoposide, Ifosfamide 0
6/03 0 Chemotherapy 3 0 0
7/03 CT Chemotherapy 4 0 Questionable 6cm mass on pancreas
7/29/03 MRI 0 0 Tumors in lympth nodes by pancreas
8/31/03 CT Chemotherapy 5 0 Tumors still there, not growing, but not shrinking either.
9/03 0 Chemotherapy 6 0 0
10/03 0 Chemotherapy 7 0 0
11/03 0 Chemotherapy 8 0 0
12/03 CT Chemotherapy 9 0 Tumors stable, not growing, not shrinking
1/04 0 Chemotherapy 10 0 End chemo
2/23/04 0 Debulking surgery 0 Removed one fist size tumor and five smaller ones. Clinically disease free.
3/04 0 0 0 0
4/04 0 0 0 0
5/24/04 CT 0 0 No tumors. No evidence of disease.
6/04 0 0 0 0
7/04 0 0 0 0
8/30/04 CT 0 0 No evidence of disease
9/04 0 0 0 0
10/04 0 0 0 0
11/04 0 0 0 0
12/22/04 CT 0 0 Relapse: tumors reappear. 4.5 cm tumor in chest between lungs. Some tumors involving lymph nodes behind stomach.
1/05 0 0 0 0
2/05 0 0 0 0
3/30/05 0 0 0 Doctors suspect disease is in lympth nodes and spredding.
4/05 0 0 0 0
5/05 0 0 0 0
6/28/05 CT Clinical Trial - AP23573 Rapamycin Tumors stable
7/05 0 Clinical trial - AP23573 Rapamycin 0
8/05 CT Clinical trial - AP23573 Rapamycin Tumors stable
9/05 0 Clinical trial - AP23573 Rapamycin 0
10/5/05 CT Clinical trial - AP23573 Rapamycin Tumor that is wrapped around main artery shrinking from 4.2 cm to 3.2 cm. Others stable
11/05 0 Clinical trial - AP23573 Rapamycin 0
12/29/05 CT Clinical trial - AP23573 Rapamycin Tumor still shrinking.
1/29/06 CT Clinical trial - AP23573 Rapamycin Tumor stable, not growing or shrinking
2/06 0 Clinical trial - AP23573 Rapamycin 0
3/06 0 Clinical trial - AP23573 Rapamycin 0
4/06 0 Clinical trial - AP23573 Rapamycin 0
5/06 0 Clinical trial - AP23573 Rapamycin 0
6/06 0 Clinical trial - AP23573 Rapamycin 0
7/06 0 Clinical trial - AP23573 Rapamycin 0
7/31/06 CT Clinical trial - AP23573 Rapamycin Tumors still stable after 14 months on Rapamycin
8/06 0 Clinical trial - AP23573 Rapamycin 0
9/06 0 Clinical trial - AP23573 Rapamycin 0
10/06 0 Clinical trial - AP23573 Rapamycin 0
11/06 0 Clinical trial - AP23573 Rapamycin No new growth. Some tumors smaller, some the same.
12/06 CT Clinical trial - AP23573 Rapamycin Tumors shrinking. Down to 10% since last scan. Total of 20% since starting Rapamycin.
1/07 0 Clinical trial - AP23573 Rapamycin 0
2/07 0 0 0 0
3/07 0 0 0 0
4/07 0 0 0 0
5/07 0 0 0 0
6/07 0 0 0 0
7/07 0 0 0 0
8/07 0 0 0 0
9/07 0 0 0 0
10/07 0 0 0 0
11/07 0 0 0 0
12/07 0 0 0 0
1/08 0 0 0 0
2/08 0 0 0 0
3/08 0 0 0 0
4/08 0 0 0 0
5/08 0 0 0 0
6/08 0 0 0 0
7/08 0 0 0 0
8/08 0 0 0 0
9/08 0 0 0 0
10/08 0 0 0 0
11/20/08 0 0 0 Passed away


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