- Alice Marano as Lois Griffin
- Darlene Davis as Meg Griffin
- Henry Greene as Peter Griffin
- Roy Knox as Chris Griffin
- Yon Greene as Dr. Amanda Rebecca
- Nick Parks as Brian Griffin
- Doug Davis as Mort Goldman
- Beth Ann Gardener as Jillian
- Bill Marano as Glenn Quagmire
- Chief Detective Jagkrit as Joe Swanson
- Jason as Dr. Hartman
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