- Mater as Sawyer Nelson
- Samantha (from Alvin and the Chipmunks: The Road Chip) as Lorraine Nelson
- Holley Shiftwell as Hazel Haskett
- Lightning McQueen as Dr. Clay Haskett
- Yar (from Disney's Dinosaur) as Dr. Cameron McCarthy
- Homer Simpson (from The Simpsons) as Kyle Connellan
- Sally as Winter
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