- Maddy Phillips as Karen
- Austin as Spongebob
- Gus as Patrick Star
- Molly Phillips as Sandy Cheeks
- Tom Philips as Squidward Tentacles
- Max Philips as Mr. Krabs
- Al Hartman as Plankton
- Ferrell as King Neptune
- Donald Brisbane as Mermaid Man
- Chad as Larry the Lobster
- Sharon as Mindy Mermaid
- Skip as Patchy the Pirate
- Nurse as Mrs. Betsy Krabs
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