- Rudy as Spongebob
- Blocky as Patrick
- Robot Jones (from Whatever Happened To Robot Jones?) as Squidward
- Brad (from My Life as a Teenage Robot) as Mr. Krabs
- Penny as Sandy
- Waffle, Gordon, & Mr. Blik (from Catscratch) as Gary
- Bessie Higgenbottom (from The Mighty B!) as Pearl
- Angelica (from Rugrats) as Mrs. Puff
- Mojo Jojo (from The Powerpuff Girls) as Plankton
- Rolf (from Ed Edd n Eddy) as Larry
- Sarah (from Ed Edd n Eddy) as Karen (Plankton's Computer Wife)
- Eddy's Brother (from Ed Edd n Eddy) as Dennis
- Human Kimberly (from Catscratch) as Mindy
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