- Charlie Chan as Sonic
- Yvonne Roland as Amy Rose
- Betty Adams as Cream
- Richard Masters as Antoine
- Lee Chan as Tails
- Arthur Hughes as Big the Cat
- Mr. Cartwright as King Acorn
- Charlie Chan, Jr. as Rotor
- Mr. Hopkins as Captain Rescue
- Honorable Charles Zaraka as Shadow
- Inspector Strasser as Knuckles
- Dr. Burton as Vector
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