- Numbuh 1 as Doraemon
- Numbuh 2 as Nobita/Noby
- Numbuh 5 as Shizuka/Sue
- Numbuh 60 as Takeshi/Big G
- Numbuh 4 as Suneo/Sneech
- Numbuh 3 as Dorami
- Bradley as Mini Dora
- Chad Dickson as Hidetoshi/Ace
- Lizzie Devine as Jaiko/Little G
- Maurice as Nobisuke Nobi/Toby
- Genki Sanban as Nobi Tamako/Tammy
- Tommy Gilligan as Sewashi/Soby
- Dr. Lincoln as Sensei Ganari/Mr. S
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