- Homer (from The Simpsons) as Alvin
- The Man in the Yellow Hat as Simon
- Curious George as Theodore
- Doctor Baker as Dave (they both start with D)
- Mr. Mean (from Mr. Men) as Ian
- Marge (from The Simpsons) as Brittany (Marge and Brittany are both girlfriends to Homer and Alvin)
- Kayla as Jeanette (Kayla and Jeanette are both girlfriends to The Man in the Yellow Hat and Simon)
- Betsy as Eleanor (Betsy and Eleanor are both girlfriends to Curious George and Theodore)
- Madame Gasket (from Robots) as Zoe
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