- Matt as Fry and Lars
- Hello Nurse (from Animaniacs) as Dr. Cahill
- Ledge as Barbados Slim
- Spongebob (from Spongebob) as Yancy Fry
- Batman (from Batman) as Al Gore
- Mr. Grumpy (from Mr. Men) as Mr. Pannuci
- Eddy (from Ed, Edd, n Eddy) as Nudar
- Waffle (from Catscratch) as Schlump
- Gordon (from Catscratch) as Flep
- Jafar (from Aladdin) as Robot Santa
- Captain Hook (from Peter Pan) as Kwanza Bot
- Gaston (from Beauty and the Beast) as Hannukah Zombie
- Arthur Read (from Arthur) as Cubert
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