- Jervis Pendleton III as Peter Griffin
- Julie Andre as Lois Griffin
- Linda Pendleton as Meg Griffin
- Alicia Pritchard as Dr. Amanda Rebecca
- Griggs as Mayor Adam West
- Sally McBride as Jillian
- Ambassador Alexander Williamson as Dr. Hartman
- Gertrude Pendleton as Connie D'Amico
- Jimmy McBride as Cleveland Brown
- and more
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