- Rowley as Hiro Hamada
- Homer Simpson (from The Simpsons) as Baymax
- Greg as Tadashi
- Mr. Jefferson as Wasabi-No-Ginger
- Susan as Honey Lemon
- Marge (from The Simpsons) as GoGo Tomago
- Roderick as Fred
- Captain Gutt (from Ice Age: Continental Drift) as Robert Callaghan
- Mrs. Jefferson as Cass
- Mrs. Burns (from The Simpsons) as Alistair Krei
- Ian (from Alvin and the Chipmunks) as Yokai
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