- Rowley Jefferson as Hiro Hamada
- Frank Heffley as Baymax
- Grey Heffley as Tadashi
- Mr. Jefferson as Wasabi-No-Ginger
- Holly Hills as Honey Lemon
- Lois Griffin (from Family Guy) as GoGo Tomago
- Rodrick Heffley as Fred
- Mr. Gerabit as Robert Callaghan
- Ashley (from Alvin and the Chipmunks: The Road Chip) as Cass
- Miles (from Alvin and the Chipmunks: The Road Chip) as Alistair Krei
- Agent Suggs (from Alvin and the Chipmunks: The Road Chip) as Yokai
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