- Frank Heffley as Wreck-It Ralph
- Greg Heffley as Fix-It Felix Jr.
- Holly Hills as Sergent
- Lois Griffin (from Family Guy) as Vanellope
- Rodrick Heffley as Gene
- Rowley Jefferson as Q*Bert
- Peter Griffin (from Family Guy) as Sonic
- Ned Flanders (from The Simpsons) as Roy
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