- Doc (from The 7D) as Papa Smurf
- Isabella Garcia-Shapiro (from Phineas and Ferb) as Smubrfette
- Scooby-Doo (from Scooby-Doo) as Clumsy Smurf
- Pac-Man (from Pac-Man and the Ghostly Adventures) as Gutsy Smurf
- Grumpy (from The 7D) as Grouchy Smurf
- Porky Pig (from Looney Tunes) as Brainy Smurf
- Yogi Bear (from Yogi Bear) as Baker Smurf
- Lincoln Loud (from The Loud House) as Narrator Smurf
- Chris McLean (from Total Drama) as Gargamel
- Jerry the Platypus (from Phineas and Ferb) as Azarel
- Marco Diaz (from Star vs. the Forces of Evil) as Patrick
- Star Butterfly (from Star vs. the Forces of Evil) as Grace
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