• Dr. John Dolittle as Bernard
  • Grandpa Archer Dolittle as Evinrude
  • Dr. Mark Weller as Luke
  • Calloway as Rufus
  • Lucky the Dog as Gramps
  • Rodney the Guinea Pig as TV Announcer
  • Lisa Dolittle as Miss Bianca
  • Rat #1 as Nero
  • Rat #2 as Brutus
  • Skunk as Mr. Snoops
  • and more

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