- Sarah Hall-Small as Matilda
- Daisy-Head Mayzie as Miss Honey
- Jane Kangaroo as Miss Trunchbull
- Cindy Lou Who as Amanda Thripp
- The Cat in the Hat as Narrator
- Pam-I-Am as Lavender
- Sam-I-Am as Charlie
- Joan as Mrs. Thelps
- Mr. Knox & Fox in Socks as The FBI Agents
- The Grinch as Harry Wormwood
- Norval the Fish as Mike Wormwood
- Aunt Myrtle as Cookie
- Izzy as Zinnia Wormwood
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