- Brian Taylor as The Cat in the Hat
- Miguel "Mike" Zavala as Sam-I-Am
- Gabby Zavala as Pam-I-Am
- Janet Taylor as Sarah Hall-Small
- Sarge as King Derwin
- Orozco as Joan
- Davis as Nick
- Van Hauser as Little Cat A
- Mr. Tre as Little Cat B
- Bonita as Jane Kangaroo
- Big Evil as The Grinch
- La La as Cindy Lou Who
- Mike Zavala's Sister as The White-Tufted Floozle Bird
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