- Holly O'Hair as Roger Rabbit
- Daring Charming as Jessica Rabbit
- Orville (from The Rescuers) as Benny the Cab
- Hunter Huntsman as Eddie Valiant
- Ashlynn Ella as Dolores
- Jafar (from Aladdin) as Judge Doom
- Cerise Hood as Smart Guy Weasel
- Raven Queen as Greasy Weasel
- Briar Beauty as Wheezy Weasel
- Madeline Hatter as Stupid Weasel
- Apple White as Psycho Weasel
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