- Peter Griffin - Robin/Dick Grayson
- Chris Griffin - Batman/Bruce Wayne
- Lois Griffin - Catwoman/Selina Kyle (I know Catwoman is bad, but Lois is seductive)
- Brian Griffin - Alfred (both loyal)
- Stewie Griffin - Penguin (both small and evil)
- Ernie the Giant Chicken - Joker (the giant chicken and Joker are the main villains)
- Connie D'Amico - Poison Ivy
- Joe - Commissioner Gordon
- Cleveland Brown - Lucius Fox
- Quagmire - Dr. Jonathan Crane/The Scarecrow
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