- Mort as Dr. Clay
- Edna Krabappel (from The Simpsons) as Lorraine
- Chris as Sawyer
- Meg as Hazel
- Stewie as Reed
- Joe as Dr. McCarthy
- Brian as Caleb
- Luann Van Houten (from The Simpsons) as Julia
- Maggie (from The Simpsons) as Mandy
- Peter as Kyle
- Barney Gumble (from The Simpsons) as Troy
- Maude Flanders (from The Simpsons) as Winter
- Lois as Hope (dolphin)
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