• Brian as Manny
  • Peter as Sid
  • Joe as Diego
  • Chris as Scrat
  • Jillian as Ellie
  • Lenny & Carl (from The Simpsons) as Crash & Eddie
  • Alissa Taylor (from The Simpsons) as Peaches
  • Maude Flanders (from The Simpsons) as Shria
  • Lois as Granny
  • Herbert as Buck
  • Barney (from The Simpsons) as Neil deBuck Weasel
  • Professor Frinks (from The Simpsons) as Julian
  • Cleveland as Shangri Llama
  • Meg as Brooke
  • Maggie (from The Simpsons) as Francine
  • Stewie as Roger
  • Death as Gavian

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