- Fanboy as Shaggy (Fanboy and Shaggy are both Wearing Green and They are both The Main Heroes)
- Chum Chum as Scooby-Doo (Chum Chum and Scooby-Doo are both Sidekicks To Fanboy and Shaggy)
- Yo as Daphne (Yo and Daphne are both Wearing Pink and They are both Beautiful)
- Kyle Bloodworth-Thomason as Fred
- Lupe as Velma (Lupe and Velma are both Have Brown Hair)
- Sigmund The Sorcerer as Dr. Phineas Phibes (Sigmund The Sorcerer and Dr. Phineas Phibes are both German, They both Have Platinum Blonde Hair and They are both Voiced By Jeff Glen Bennett)
- Oz as Uncle Albert (Aka Dr. Trebla)
- Lenny Flynn-Boyle as Agent 1
- Boog Shlizetti as Agent 2 (Boog Shlizetti are Agent 2 are both Voiced By Jeff Glen Bennett)
- Marsha as Misty Swiss (Marsha and Misty Swiss are both Villainess and Their Names Begins With a M)
- Copy Kitten as Cat Lady
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