- Fanboy as Roger Rabbit
- Yo as Jessica Rabbit
- Chum Chum as Baby Herman
- Oz Harmounian as Eddie Valient
- Nurse Lady Pam as Dolores
- Lupe as Lena Hyena
- Francine as Betty Boop
- Global Warmer as Judge Doom
- Kyle Bloodworth-Thomason as Smarty
- Sigmund The Sorcerer as Greasy
- Lenny Flynn-Boyle as Psycho
- Marsha as Wheezy
- Boog Shlizetti as Stupid
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