- Mr. Fantastic as Steve
- Horton (from Horton Hears a Who) as Joe
- Susie (from Family Guy) as Tickety Tock
- Chris (from Family Guy) as Slippery Soap
- Gabato (from Journey 2: The Mysterious Island) as Mr. Salt
- Invisible Woman as Mrs. Pepper
- Joe (from Family Guy) as Mailbox
- Dr. Doom as Shovel
- Meg (from Family Guy) as Pail
- Thing as Tyrese Gibson
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