- Valerie as Dr. Evil
- Heinrich Von Marzipan as Frau Farbissina (Heinrich Von Marzipan and Frau Farbissina are both Germans)
- Numbuh 5 as Austin Powers
- Numbuh 2 as Foxxy Cleopatra (Numbuh 2 and Foxxy Cleopatra are both Americans)
- Mike Myers - Valerie and Numbuh 5
- Mindy Sterling - Heinrich Von Marzipan
- Beyonce Knowles - Numbuh 2
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