Galaxy Trek (Sacagawea) tells about the adventures of the Grey Wolf-class freighter Sacagawea commanded by captain Kasidy Yates.
- Kasidy Yates: Captain of the Sacagawea.
- Pardshay: Pilot of the Sacagawea.
- Gornock: Medical mind on the Sacagawea.
- Kilby: Kilby is a Kobok who serves as second Pilot on the Sacajawea.
- Chris: Chief Engineer on the Sacajawea.
- Galonmor: A man who serves on board the Sacagawea as an engineer.
- Chmee: Chmee is a Kzinti telepath who defected to the Earth Confederation because he didn't want to take the drug. He now serves on the Sacajawea as the ships translator.
- T8-Y4 and T8-Y5: Two droids who serve as the Matienance crew on the Sacajawea.
- Halogon: Harlogon serves as the ships navigator and scout.
- Fasdono: Fasdono serves on the Sacajawea as the Ships cook.