- Jon Arbuckle as Homer Simpson
- Garfield as Bart Simpson
- Dr. Liz Wilson as Marge Simpson
- Happy Chapman as Mr. Burns
- Happy's butler as Snake Jailbird
- Christopher Merllo as Otto
- Mrs. Baker as Sherri
- Little Girl as Terri
- Raccoon Lodge Member as Dr. Julius Hibbert
- News Reporter as Waylon Smithers, Jr.
- Engineer as Grandpa Abe Simpson
- Louis as Ralph Wiggum
- Lucas as Barney Gumble
- Arlene as Bernice Hibbert
- Dad Rat as Chief Clancy Wiggum
- Mom Rat as Selma Bouvier
- Spanky as Hiro
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