- James Brown as Homer SImpson
- Bobby Byrd as Bart Simpson
- Ben Bart as Ned Flanders
- Susie Brown as Lisa Simpson
- Baby Roy as Kent Brockman
- Joseph "Joe" James as Dr. Julius Hibbert
- Syd Nathan as Barney Gumble
- Meaceo Parker as Principal Seymour Skinner
- Deidre Jenkins as Allison Taylor
- Ralph Bass as Mayor Joe Quimby
- Yvonne Fair as Marge Simpson
- Vicki Anderson as Bernice Hibbert
- Pee Wee Ellis as Waylon Smithers, Jr.
- and more
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