- Johnny Blaze / Ghost Rider as Bart Simpson
- Roxanne Simpson as Lisa Simpson
- Mephistopheles as Homer Simpson
- Blackheart / Legion as Grandpa Abe Simpson
- Carter Slade / Caretaker as Mr. Burns
- Young Johnny Blaze as Itchy
- Young Roxanne Simpson as Marge Simpson
- Barton Blaze as Snake Jailbird
- Mack as Scratchy
- Team Blaze as Krusty the Clown
- Captain Dolan as Ralph Wiggum
- Girl in Alley as Edna Krabbappel
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