- Gerald O'Hara as Homer Simpson
- Barbara O'Neil as Marge Simpson
- Scarlett O'Hara as Lisa Simpson
- Rhett O'Hara as Bart Simpson
- Carreen O'Hara as Edna Krabappel
- Suellen O'Hara as Patty Bouvier
- Brent Tarleton as Grandpa Abe Simpson
- Stuart Tarleton as Snake Jailbird
- Mammy as Maggie Simpson
- Pork as Otto
- and more
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