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Groups by Chemotherapy

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[edit] First Line Chemotherapy

A. Original P6 = 7 cycles of high dose chemo:

Cycle: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine with Mesna
Cycle: Etoposide (VP-16); Ifosfamide
Image:Tinysunfl.jpgBender, Michael
Image:Tinysunfl.jpgBidleman, Shawn
Image:Tinysunfl.jpgDaunoras, Jay
Image:Tinysunfl.jpgDeWalle, Mark
Image:Tinysunfl.jpgHendricks, Haley
Image:Tinysunfl.jpgHobbs , Caleb
Image:Tinysunfl.jpgJenkins , Craig
Image:Tinysunfl.jpgLunchuck, Timothy
Image:Tinysunfl.jpgMays, Timothy
Image:Tinysunfl.jpgSchaut , Nikki
Image:Tinysunfl.jpgSellers, Adam
Image:Tinysunfl.jpgVoss, Ken
Image:Tinysunfl.jpgWebber, Gerry
1. Modified by Dr Kushner
Image:Tinysunfl.jpgAdomanis, Jeff
2. Altered P6
VACIME - Vincristine; Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Ifosfamide; Mesna; and Etoposide (VP-16), at very high doses.
Image:Tinysunfl.jpgBerman, Richard
3. Modified P6
Image:Tinysunfl.jpgBishnow, Brian
4. P6 Variation - 6 cycles
Cycle: Ifosfamide, Etoposide - 2 cycles
Cycle: Vincristine, Doxorubicin, Cyclophosphamide - 4 cycles
Image:Tinysunfl.jpgOberholzer, Chris
5. Variation of P6 - More sessions and lower than recommended dosage
4 Cycles: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine
3 Cycles: Etoposide (VP-16), Ifosfomide
Image:Tinysunfl.jpgSmith, Pamela

B. Kushner's DSRCT P6 Variation (Pediatric) = 6 cycles of high dose chemo

Cycle 1,2,3,6 = Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
Cycle 4, 5= Cytoxan(Cyclophosphamide) and Topotecan
Image:Tinysunfl.jpgBrill, Steven
Image:Tinysunfl.jpgPusey, Jade
Image:Tinysunfl.jpgReichle, Brian
Image:Tinysunfl.jpgWilson, Derek
1. Variation of Kushner's P6 = 7 cycles
Cycle 1, 5, 6, 7: Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
Cycle 2: Etoposide (VP-16) and Ifosfamide (Ifex)
Cycle 3, 4: Cytoxan (Cyclophosphamide) and Topotecan
Image:Tinysunfl.jpgWilson, Derek
2. Variation of Kushner's P6
Cyle 1,2,3 : Adriamycin (Doxorubicin); Ifosfamide, and Vincristine
Cycle 4,5,6,9: Etoposide(VP-16); Ifosfamide
Cycle 7,8 : Cytoxan(Cyclophosphamide) and Topotecan
Image:Tinysunfl.jpgBudimir-Hussey, Jordan
3. Variation of Kushner's P6
Cycle 1, 2, 3, 4, 5: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide) and Vincristine
Cycle 6, 7, 8, 9: Etoposide(VP-16); Ifosfamide
Cycle 10, 11 Topotecan everyday for 2 weeks
Image:Tinysunfl.jpgCarfi, Christopher
4. Variation of Kushner's P6
Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine; Topotecan, with Mesna
Image:Tinysunfl.jpgShield, Jasmine


C. P6 'Adult' Variation = based on Original P6 but with a longer time frame (10-14 cycles) and lower doses and sometimes without the Etoposide (VP-16) and Ifosomide.


D. Ewings Protocol (based on same 5 drugs as Original P6 but with a different time frame of 8 or more cycles and lower dosage of Cytoxan(Cyclophosphamide) and Ifosomide).

Image:Tinysunfl.jpgRobertson , Nathan

[edit] First Line Other Chemo Combinations

1. Adriamycin (Doxorubicin); Cisplatin; Etoposide(VP-16); Ifosfamide; and Vincristine

Image:Tinysunfl.jpgAbram, Jerry

2. Adriamycin (Doxorubicin); Cisplatin, Paclitaxel, Ifosfamide with Mesna

Image:Tinysunfl.jpgCorry, Nicola

3. Cycle: Adriamycin (Doxorubicin); Cisplatin; Vincristine

Cycle: ICE = Ifosmoside; Carboplatin; Etoposide
Image:Tinysunfl.jpgHickie, Dustin

4. Cycle: Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Cisplatin

Cycle: ICE = Ifosmoside; Carboplatin; Etoposide
Image:Tinysunfl.jpgDenault, David

5. Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Etoposide(VP-16); Ifosfamide;

Image:Tinysunfl.jpgWilson, Michael

6. Adriamycin(Doxorubicin); Cytoxan(Cyclophosphamide); and Vincristine

Image:Tinysunfl.jpgMurray , Sheila
Image:Tinysunfl.jpgLiles, Nikole

7. Cycle: Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Vincristine

Cycle: Cisplatin; Etoposide; Ifosfomide
Image:Tinysunfl.jpgGibson, Sarah Taylor

8. Cyle: Adriamycin (Doxorubicin); Etoposide(VP-16); Ifosfamide, and Vincristine (VIDE - 6 rounds)

Cycle: Vincristine, Ifosfamide, Etoposide (VIE - 7 rounds)
Cycle: Etoposide and Cytoxan (Cyclophosphamide) - (1 round)
Image:Tinysunfl.jpgBroude, Robert

9. Cyle: Adriamycin (Doxorubicin); Etoposide(VP-16); Ifosfamide, and Vincristine (VIDE - 6 rounds)

Image:Tinysunfl.jpgMiddelman, Erik

10. Adriamycin (Doxorubicin); Ifosfamide (Ifex)

Image:Tinysunfl.jpgScranton, Patrick

11. Adriamycin(Doxorubicin); Ifosfamide(Ifex); and Vincristine

Image:Tinysunfl.jpgCloer, Rebecca

12. Adriblastin (Doxorubicin) (4 days); Ifosfamide(Ifex) (3 days), Platinol (Cisplatin) (1 day) - 4 day cycles

Image:Tinysunfl.jpgSchlegel, Maria

13. Asparaginase; Dactinomycin (Actinomycin D); Hydroxyurea

Image:Tinysunfl.jpgMartinson, Chad

14. Bleomycin; Etoposide(VP-16); Cisplatinum

Image:Tinysunfl.jpgBerman, Richard
Image:Tinysunfl.jpgStanley, Dave

15. Carboplatin; Dactiamycin; Epirubicin; Etoposid; Ifosfamide(Ifex); and Vincristine

Image:Tinysunfl.jpgKiyici , Michael

16. Carboplatinum and Gemzar

Image:Tinysunfl.jpgHodges, Marlena

17. Cisplatin; Decadron; Epirubicin; Etoposide(VP-16); Ifosfamide(Ifex); D545 with Mesna Vincristine;

Image:Tinysunfl.jpgZucca , David

18. Docetaxel (Taxotere) and Gemcitabine (Gemzar)

Image:Tinysunfl.jpgParrish, Joshua

19. Cycle: Epirubicin, Ifosfamide(Ifex) with Mesna, Vincristine

Cycle: Cisplatinum; Etoposide
Image:Tinysunfl.jpgMouktaroudes, Christos

20. Adriamycin (Doxorubicin); Imatinib mesylate (Gleevac), Vinblastin

F. Other First Line Drugs

1. Carboplatin

Image:Tinysunfl.jpgMartinson, Chad


2. Vinblastin

[edit] Second Line Chemotherapy

A. Cycles: Adriamycin (Doxorubicin, Doxil); Cytoxan(Cyclophosphamide); Vincristine

Cycles: Etoposide (VP-16); Ifosfamide (Ifex)
Image:Tinysunfl.jpgSchafer, Ryan

B. Adriamycin (Doxorubicin, Doxil) and Ifosfamide (Ifex)

Image:Tinysunfl.jpgBender , Michael
Image:Tinysunfl.jpgWilson, Derek

C. Carboplatin; Cytoxan(Cyclophosphamide); Etoposide(VP-16) - 4 Cycles

Image:Tinysunfl.jpgSchafer, Ryan

D. Carboplatin and Paclitaxel (Taxol)

Image:Tinysunfl.jpgDenault, David

E. Cisplatin; Paclitaxel (Taxol)

Image:Tinysunfl.jpgSmith, Pamela

F. Cytoxan(Cyclophosphamide); Etoposide (VP-16); (High dose for stem cell transplant)

Image:Tinysunfl.jpgGibson, Sarah Taylor

G. Cytoxan(Cyclophosphamide) and Topotecan (Hycamtin)

Image:Tinysunfl.jpgHickie, Dustin

H. Imatinib mesylate (Gleevec) and Temozolomide (Temodar)

Image:Tinysunfl.jpgCarfi, Christopher

I. ICE = Ifosfamide (Ifex), Carboplatin, Etoposide (VP-16)

Image:Tinysunfl.jpgCarfi, Christopher
Image:Tinysunfl.jpgDenault, David

J. Irinotecan(Camptosar)and Temodar (Temozolimide)

Image:Tinysunfl.jpgRobertson, Nathan
Image:Tinysunfl.jpgJenkins , Craig
Image:Tinysunfl.jpgPusey, Jade
Image:Tinysunfl.jpgBodjanac, Nicole

K. Irinotecan (Camptosar) and oral Xeloda

Image:Tinysunfl.jpgCarfi, Christopher

L. Sutent (Sunitinib malate)

Image:Tinysunfl.jpgRicardo F
Image:Tinysunfl.jpgDeWalle, Mark
Image:Tinysunfl.jpgHahn, Tim
Image:Tinysunfl.jpgSkurat, Steven

L. VICE = Vincristine, Ifosfamide (Ifex), Cisplatin, and Etoposide(VP-16)

Image:Tinysunfl.jpgSellers, Adam

M. VIP-E - Etoposide (VP-16), Ifosfamide, Cisplatin, and Epirubicin

N. Sorafenib tosylate (Nexavar)

[edit] Third Line and Other Chemo Combinations

A. Adriamycin (Doxorubicin), Cyclophosphamide (Cytoxin), Vincristine (higher dosage).

Image:Tinysunfl.jpgCarfi, Christopher

B. Adriamycin (Doxorubicin)(Doxil) and Thalidomide

Image:Tinysunfl.jpgDaunoras, Jay

C.Alimta and Cisplatnum

Image:Tinysunfl.jpgOtt, Keegan

D. Cycle: Bleomycin; Cisplatin; Methotrexate; Vincristine

Cycle: Actinomycin D; Cytoxan (Cyclophosphamide); Vincristine
Image:Tinysunfl.jpgSchafer, Ryan

E. Bexarotene (Targretin) and ICE protocol : Ifosfamide, Carboplatin, Etoposide

Image:Tinysunfl.jpgDaunoras, Jay

F. Bexarotene (Targretin) and ICE protocol , Thalidomide

Image:Tinysunfl.jpgDaunoras, Jay

G. CCT High-dose chemotherapy

Cyclophosphamide (Cytoxan) 1500 mg/m2
Carboplatin 200 mg/m2
Thiotepa 125 mg/m2

H. Carboplatin and Thiotepa (high dose chemotherapy for stem cell)

Image:Tinysunfl.jpgDaunoras, Jay
Image:Tinysunfl.jpgLunchuck, Timothy

I. Cycle: Carboplatin and Paclitaxel (Taxol)

Cycle: Adriamycin
Image:Tinysunfl.jpgDenault, David

J. Carboplatin; Thiotepa; Topotecan; - Stem Cell rescue

Image:Tinysunfl.jpgShield, Jasmine


K. Casodex (hormonal therapy drug)and Thalidomide

Image:Tinysunfl.jpgCarfi, Christopher

L. Celebrex, oral Cyclophosphamide (Cytoxin), oral Etoposide (VP-16), Thalidomide ,

Image:Tinysunfl.jpgCarfi, Christopher

M.Cisplatnum and Etoposide (VP-16)

Image:Tinysunfl.jpgCloer, Rebecca

N. Cisplatin and Irinotecan (Camptosar)

Image:Tinysunfl.jpgMartinson, Chad

O.Cyclophosphamide (Cytoxan) and Topotecan

Image:Tinysunfl.jpgRobertson,Nathan

P. Cyclophosphamide (Cytoxan); Thiotepa

Image:Tinysunfl.jpgMartinson, Chad

Q. Dactinomycin (Actinomycin), Ifosfamide (Ifex), Vincristine

Image:Tinysunfl.jpgCarfi, Christopher

R.Docetaxel (Taxotere) and Gemcitabine (Gemzar)

Image:Tinysunfl.jpgCloer, Rebecca

S. Etoposide (Oral VP16), Thalidomide, Lupron

Image:Tinysunfl.jpgDaunoras, Jay

T. Methotrexate with Leucovorin

Image:Tinysunfl.jpgMartinson, Chad

[edit] Single Chemotherapies

1. Actinomycin(Dactinomycin)

2. Adriamycin (Doxorubicin)(Doxil)

Image:Tinysunfl.jpgDaunoras, Jay

3. Alimta

4. Bexarotene (Targretin)

Image:Tinysunfl.jpgDaunoras, Jay

5. Casodex (Bicalutamide) - hormonal therapy used in prostrate cancer.

6. Capecitabine

7. Celebrex (Celecoxib)

8. Cytoxan (Cyclophosphamide)

Image:Tinysunfl.jpgDenault, David

9. Decitabine

Image:Tinysunfl.jpgWilson, Derek

10. Doxil - (doxorubicin HCl liposome injection}

11. Etoposide (Oral VP16)

Image:Tinysunfl.jpgDaunoras, Jay

12. Gleevec - see Targeted therapies


13. Gemcitabine ( Gemzar )

Image:Tinysunfl.jpgBishnow, Brian
Image:Tinysunfl.jpgDaunoras, Jay
Image:Tinysunfl.jpgMartinson, Chad
Image:Tinysunfl.jpgScranton, Patrick

14. Altretamine (Hexalen)

Image:Tinysunfl.jpgSmith, Pamela


15. Irinotecan

Image:Tinysunfl.jpgCloer, Rebecca
Image:Tinysunfl.jpgBishnow, Brian
Image:Tinysunfl.jpgWilson, Derek

16. Lupron

Image:Tinysunfl.jpgCarfi, Christopher
Image:Tinysunfl.jpgDaunoras, Jay

17. Sirolimus (Rapamycin)

Image:Tinysunfl.jpgDaunoras, Jay

18. Thiotepa

Image:Tinysunfl.jpgDenault, David

19. Thalidomide

Image:Tinysunfl.jpgWilson, Derek

20. Topetecan

Image:Tinysunfl.jpgSellers, Adam

21. Velcade (Bortezomib)

Image:Tinysunfl.jpgMartinson, Chad

22. Vinblastine (Velban)

Image:Tinysunfl.jpgBodjanac, Nicole

[edit] Targeted Therapies

1. Imatinib mesylate also called Gleevec and STI-571

Image:Tinysunfl.jpgSchaut, Nikki
Image:Tinysunfl.jpgWilson, Derek
Image:Tinysunfl.jpgLiles, Nikole

2. Sorafenib also called Nexavar

Image:Tinysunfl.jpgByrd, David

3. Sunitinib also called Sutent and SU11248

Image:Tinysunfl.jpgDeWalle, Mark
Image:Tinysunfl.jpgHobbs, Caleb
Image:Tinysunfl.jpgRobertson, Nathan
Image:Tinysunfl.jpgSkurat, Steven

[edit] Clinical Trials

See Groups by Clinical Trial

[edit] DSRCT References

Contact: dsrct.wiki@gmail.com

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