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Groups by Chemotherapy

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First Line Chemotherapy

A. Original P6 = 7 cycles of high dose chemo:

Cycle: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine with Mesna
Cycle: Etoposide (VP-16); Ifosfamide
TinysunflBender, Michael
TinysunflBidleman, Shawn
TinysunflDaunoras, Jay
TinysunflDeWalle, Mark
TinysunflHendricks, Haley
TinysunflHobbs , Caleb
TinysunflJenkins , Craig
TinysunflLunchuck, Timothy
TinysunflMays, Timothy
TinysunflSchaut , Nikki
TinysunflSellers, Adam
TinysunflVoss, Ken
TinysunflWebber, Gerry
1. Modified by Dr Kushner
TinysunflAdomanis, Jeff
2. Altered P6
VACIME - Vincristine; Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Ifosfamide; Mesna; and Etoposide (VP-16), at very high doses.
TinysunflBerman, Richard
3. Modified P6
TinysunflBishnow, Brian
4. P6 Variation - 6 cycles
Cycle: Ifosfamide, Etoposide - 2 cycles
Cycle: Vincristine, Doxorubicin, Cyclophosphamide - 4 cycles
TinysunflOberholzer, Chris
5. Variation of P6 - More sessions and lower than recommended dosage
4 Cycles: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine
3 Cycles: Etoposide (VP-16), Ifosfomide
TinysunflSmith, Pamela

B. Kushner's DSRCT P6 Variation (Pediatric) = 6 cycles of high dose chemo

Cycle 1,2,3,6 = Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
Cycle 4, 5= Cytoxan(Cyclophosphamide) and Topotecan
TinysunflBrill, Steven
TinysunflPusey, Jade
TinysunflReichle, Brian
TinysunflWilson, Derek
1. Variation of Kushner's P6 = 7 cycles
Cycle 1, 5, 6, 7: Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
Cycle 2: Etoposide (VP-16) and Ifosfamide (Ifex)
Cycle 3, 4: Cytoxan (Cyclophosphamide) and Topotecan
TinysunflWilson, Derek
2. Variation of Kushner's P6
Cyle 1,2,3 : Adriamycin (Doxorubicin); Ifosfamide, and Vincristine
Cycle 4,5,6,9: Etoposide(VP-16); Ifosfamide
Cycle 7,8 : Cytoxan(Cyclophosphamide) and Topotecan
TinysunflBudimir-Hussey, Jordan
3. Variation of Kushner's P6
Cycle 1, 2, 3, 4, 5: Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide) and Vincristine
Cycle 6, 7, 8, 9: Etoposide(VP-16); Ifosfamide
Cycle 10, 11 Topotecan everyday for 2 weeks
TinysunflCarfi, Christopher
4. Variation of Kushner's P6
Adriamycin (Doxorubicin); Cytoxan (Cyclophosphamide); Vincristine; Topotecan, with Mesna
TinysunflShield, Jasmine


C. P6 'Adult' Variation = based on Original P6 but with a longer time frame (10-14 cycles) and lower doses and sometimes without the Etoposide (VP-16) and Ifosomide.

TinysunflOrantes, Meliza


D. Ewings Protocol (based on same 5 drugs as Original P6 but with a different time frame of 8 or more cycles and lower dosage of Cytoxan(Cyclophosphamide) and Ifosomide).

TinysunflRobertson , Nathan

First Line Other Chemo Combinations

1. Adriamycin (Doxorubicin); Cisplatin; Etoposide(VP-16); Ifosfamide; and Vincristine

TinysunflAbram, Jerry

2. Adriamycin (Doxorubicin); Cisplatin, Paclitaxel, Ifosfamide with Mesna

TinysunflCorry, Nicola

3. Cycle: Adriamycin (Doxorubicin); Cisplatin; Vincristine

Cycle: ICE = Ifosmoside; Carboplatin; Etoposide
TinysunflHickie, Dustin

4. Cycle: Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Cisplatin

Cycle: ICE = Ifosmoside; Carboplatin; Etoposide
TinysunflDenault, David

5. Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Etoposide(VP-16); Ifosfamide;

TinysunflWilson, Michael

6. Adriamycin(Doxorubicin); Cytoxan(Cyclophosphamide); and Vincristine

TinysunflMurray , Sheila
TinysunflLiles, Nikole

7. Cycle: Adriamycin (Doxorubicin); Cytoxan(Cyclophosphamide); Vincristine

Cycle: Cisplatin; Etoposide; Ifosfomide
TinysunflGibson, Sarah Taylor

8. Cyle: Adriamycin (Doxorubicin); Etoposide(VP-16); Ifosfamide, and Vincristine (VIDE - 6 rounds)

Cycle: Vincristine, Ifosfamide, Etoposide (VIE - 7 rounds)
Cycle: Etoposide and Cytoxan (Cyclophosphamide) - (1 round)
TinysunflBroude, Robert

9. Cyle: Adriamycin (Doxorubicin); Etoposide(VP-16); Ifosfamide, and Vincristine (VIDE - 6 rounds)

TinysunflMiddelman, Erik

10. Adriamycin (Doxorubicin); Ifosfamide (Ifex)

TinysunflScranton, Patrick

11. Adriamycin(Doxorubicin); Ifosfamide(Ifex); and Vincristine

TinysunflCloer, Rebecca
TinysunflBraswell , Chris

12. Adriblastin (Doxorubicin) (4 days); Ifosfamide(Ifex) (3 days), Platinol (Cisplatin) (1 day) - 4 day cycles

TinysunflSchlegel, Maria

13. Asparaginase; Dactinomycin (Actinomycin D); Hydroxyurea

TinysunflMartinson, Chad

14. Bleomycin; Etoposide(VP-16); Cisplatinum

TinysunflBerman, Richard
TinysunflStanley, Dave

15. Carboplatin; Dactiamycin; Epirubicin; Etoposid; Ifosfamide(Ifex); and Vincristine

TinysunflKiyici , Michael

16. Carboplatinum and Gemzar

TinysunflHodges, Marlena

17. Cisplatin; Decadron; Epirubicin; Etoposide(VP-16); Ifosfamide(Ifex); D545 with Mesna Vincristine;

TinysunflZucca , David

18. Docetaxel (Taxotere) and Gemcitabine (Gemzar)

TinysunflParrish, Joshua

19. Cycle: Epirubicin, Ifosfamide(Ifex) with Mesna, Vincristine

Cycle: Cisplatinum; Etoposide
TinysunflMouktaroudes, Christos

20. Adriamycin (Doxorubicin); Imatinib mesylate (Gleevac), Vinblastin

TinysunflRamsey, Zach

F. Other First Line Drugs

1. Carboplatin

TinysunflMartinson, Chad


2. Vinblastin

Second Line Chemotherapy

A. Cycles: Adriamycin (Doxorubicin, Doxil); Cytoxan(Cyclophosphamide); Vincristine

Cycles: Etoposide (VP-16); Ifosfamide (Ifex)
TinysunflSchafer, Ryan

B. Adriamycin (Doxorubicin, Doxil) and Ifosfamide (Ifex)

TinysunflBender , Michael
TinysunflWilson, Derek

C. Carboplatin; Cytoxan(Cyclophosphamide); Etoposide(VP-16) - 4 Cycles

TinysunflSchafer, Ryan

D. Carboplatin and Paclitaxel (Taxol)

TinysunflDenault, David

E. Cisplatin; Paclitaxel (Taxol)

TinysunflSmith, Pamela

F. Cytoxan(Cyclophosphamide); Etoposide (VP-16); (High dose for stem cell transplant)

TinysunflGibson, Sarah Taylor

G. Cytoxan(Cyclophosphamide) and Topotecan (Hycamtin)

TinysunflHickie, Dustin

H. Imatinib mesylate (Gleevec) and Temozolomide (Temodar)

TinysunflCarfi, Christopher

I. ICE = Ifosfamide (Ifex), Carboplatin, Etoposide (VP-16)

TinysunflCarfi, Christopher
TinysunflDenault, David

J. Irinotecan(Camptosar)and Temodar (Temozolimide)

TinysunflRobertson, Nathan
TinysunflJenkins , Craig
TinysunflPusey, Jade
TinysunflBodjanac, Nicole

K. Irinotecan (Camptosar) and oral Xeloda

TinysunflCarfi, Christopher

L. Sutent (Sunitinib malate)

TinysunflRicardo F
TinysunflDeWalle, Mark
TinysunflHahn, Tim
TinysunflSkurat, Steven

L. VICE = Vincristine, Ifosfamide (Ifex), Cisplatin, and Etoposide(VP-16)

TinysunflSellers, Adam

M. VIP-E - Etoposide (VP-16), Ifosfamide, Cisplatin, and Epirubicin

N. Sorafenib tosylate (Nexavar)

TinysunflBraswell, Chris

Third Line and Other Chemo Combinations

A. Adriamycin (Doxorubicin), Cyclophosphamide (Cytoxin), Vincristine (higher dosage).

TinysunflCarfi, Christopher

B. Adriamycin (Doxorubicin)(Doxil) and Thalidomide

TinysunflDaunoras, Jay

C.Alimta and Cisplatnum

TinysunflOtt, Keegan

D. Cycle: Bleomycin; Cisplatin; Methotrexate; Vincristine

Cycle: Actinomycin D; Cytoxan (Cyclophosphamide); Vincristine
TinysunflSchafer, Ryan

E. Bexarotene (Targretin) and ICE protocol : Ifosfamide, Carboplatin, Etoposide

TinysunflDaunoras, Jay

F. Bexarotene (Targretin) and ICE protocol , Thalidomide

TinysunflDaunoras, Jay

G. CCT High-dose chemotherapy

Cyclophosphamide (Cytoxan) 1500 mg/m2
Carboplatin 200 mg/m2
Thiotepa 125 mg/m2

H. Carboplatin and Thiotepa (high dose chemotherapy for stem cell)

TinysunflDaunoras, Jay
TinysunflLunchuck, Timothy

I. Cycle: Carboplatin and Paclitaxel (Taxol)

Cycle: Adriamycin
TinysunflDenault, David

J. Carboplatin; Thiotepa; Topotecan; - Stem Cell rescue

TinysunflShield, Jasmine


K. Casodex (hormonal therapy drug)and Thalidomide

TinysunflCarfi, Christopher

L. Celebrex, oral Cyclophosphamide (Cytoxin), oral Etoposide (VP-16), Thalidomide ,

TinysunflCarfi, Christopher

M.Cisplatnum and Etoposide (VP-16)

TinysunflCloer, Rebecca

N. Cisplatin and Irinotecan (Camptosar)

TinysunflMartinson, Chad

O.Cyclophosphamide (Cytoxan) and Topotecan

TinysunflRobertson,Nathan

P. Cyclophosphamide (Cytoxan); Thiotepa

TinysunflMartinson, Chad

Q. Dactinomycin (Actinomycin), Ifosfamide (Ifex), Vincristine

TinysunflCarfi, Christopher

R.Docetaxel (Taxotere) and Gemcitabine (Gemzar)

TinysunflCloer, Rebecca

S. Etoposide (Oral VP16), Thalidomide, Lupron

TinysunflDaunoras, Jay

T. Methotrexate with Leucovorin

TinysunflMartinson, Chad

Single Chemotherapies

1. Actinomycin(Dactinomycin)

2. Adriamycin (Doxorubicin)(Doxil)

TinysunflDaunoras, Jay

3. Alimta

4. Bexarotene (Targretin)

TinysunflDaunoras, Jay

5. Casodex (Bicalutamide) - hormonal therapy used in prostrate cancer.

6. Capecitabine

7. Celebrex (Celecoxib)

8. Cytoxan (Cyclophosphamide)

TinysunflDenault, David

9. Decitabine

TinysunflWilson, Derek

10. Doxil - (doxorubicin HCl liposome injection}

11. Etoposide (Oral VP16)

TinysunflDaunoras, Jay

12. Gleevec - see Targeted therapies


13. Gemcitabine ( Gemzar )

TinysunflBishnow, Brian
TinysunflDaunoras, Jay
TinysunflMartinson, Chad
TinysunflScranton, Patrick

14. Altretamine (Hexalen)

TinysunflSmith, Pamela


15. Irinotecan

TinysunflCloer, Rebecca
TinysunflBishnow, Brian
TinysunflWilson, Derek

16. Lupron

TinysunflCarfi, Christopher
TinysunflDaunoras, Jay

17. Sirolimus (Rapamycin)

TinysunflDaunoras, Jay

18. Thiotepa

TinysunflDenault, David

19. Thalidomide

TinysunflWilson, Derek

20. Topetecan

TinysunflSellers, Adam

21. Velcade (Bortezomib)

TinysunflMartinson, Chad

22. Vinblastine (Velban)

TinysunflBodjanac, Nicole

Targeted Therapies

1. Imatinib mesylate also called Gleevec and STI-571

TinysunflSchaut, Nikki
TinysunflWilson, Derek
TinysunflLiles, Nikole

2. Sorafenib also called Nexavar

TinysunflBraswell, Christian
TinysunflByrd, David

3. Sunitinib also called Sutent and SU11248

TinysunflDeWalle, Mark
TinysunflHobbs, Caleb
TinysunflRobertson, Nathan
TinysunflSkurat, Steven

Clinical Trials

See Groups by Clinical Trial

DSRCT References

Contact: dsrct.wiki@gmail.com

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