- Matt Drayton as Peter Griffin
- Dr. John Wayde Prentice Jr. as Brian Griffin
- Christina Drayton as Lois Griffin
- Joanna Drayton as Meg Griffin
- Mike Ryan as Chris Griffin
- Mary Prentice as Dr. Amanda Rebecca
- John Prntice Sr. as Mort Goldman
- Hilary St. George as Susie Swanson
- Carhop as Tom Tucker
- Matilda Binks as Donna Tubbs-Brown
- Dorothy as Jillian
- Frankie as Joe Swanson
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