- Sean Mercer as Kermit the Frog
- Kurt Muller as Rizzo the Rat
- Anna Maria D'Alessandro as Miss Piggy
- "Pockets" as Marvin Suggs
- Charles Maurey as Gonzo the Great
- Little Wolf as Dr. Teeth
- Brande De La Court as Crazy Harry
- Luis Francisco Garcia Lopez as Rowlf
- Dr. Sanderson as Wayne
- Nurse as Wanda
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