- Heathcliff as Wreck-it Ralph
- Rainbow Dash (from My Little Pony) as Vanellope
- Trixie (from My Little Pony) as Taffyta
- Applejack (from My Little Pony) as Rancis
- Pinkie Pie (from My Little Pony) as Candlehead
- Other Ponies (from My Little Pony) as Other Races
- Hector as Gene
- Spike as Beard Papa
- Riff Raff as Fix-It Felix, Jr.
- Cleo as Sergeant
- Leroy as King Candy/Turbo
- Sonic as Himself
- and more
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