- Claire Kubik as Misty
- Charlie Grimes as Ash Ketchum
- Tom Rubik/Ron Chapman as Pikachu
- Terence Embry as Professor Birch
- First Lieutenant Terence Embry as Brock
- Jackie Grimaldi as May
- Brigadier General Bill Marks as Todd
- Major James Hernandez as Tracey
- Major Maldron as Mewtwo
- FBI Special Agent Mullins as Meowth
- Colonel Farrell as Harley
- Troy Abbott as James
- Gracie as Jessie
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