- Charlotte Hollis as Lois Griffin
- Miriam Deering as Meg Griffin
- Dr. Drew Bayliss as Peter Griffin
- Velma Cruther as Jillian
- Harry Willis as Mayor Adam West
- Big Sam Hollis as Stewie Griffin
- Jewel Mayhew as Dr. Amanda Rebecca
- John Mayhew as Chris Griffin
- Foreman as Dr. Hartman
- Town Gossip as Susie Swanson
- Paul Merchand as Cleveland Brown
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