- Owen Chase as Kevin McCallister
- Herman Melville as Old Man Marley
- Kyle (from Dolphin Tale) as Peter McCallister
- Alexander (from Journey 2: The Mysterious Island) as Buzz
- Matthew Joy as Frank
- Captain George Pollard, Jr. as Rod
- Gabato (from Journey 2: The Mysterious Island) as Jeff
- Old Thomas Nickerson as Fuller
- Mrs. Nickerson as Linnie
- Peggy as Kate McCallister
- Paul Macy as Harry Lyme
- Lizard (from Journey 2: The Mysterious Island) as Marv Merchants
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