- Johnny Knoxville as Diddy Kong
- Kat Von D as Dixie Kong (cameo)
- Bam Margera as Pipsy
- Dave England as T.T.
- Chris Pontius as Bubbler the Octopus
- Ryan Dunn as Bluey the Walrus
- Steve-O as Conker
- Mark Zupan as Taj (cameo)
- Rip Taylor as Bumper (cameo)
- Wee-Man as Wiz Pig
- Preston Lacy as Drumstick
- Mark Zupan as Smokey the Dragon (cameo)
- and more
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