- Johnny Knoxville as Fireman Sam
- Bam Margera as Elvis Criddlington
- Steve-O as Norman Price
- Ryan Dunn as The Robot Bin
- Dave England as Bentley the Robot
- Preston Lacy as Trevor Evans
- Wee-Man as The Robot Cook
- Kat Von D as Firefighter Penny Morris (cameo)
- Rip Taylor as James (cameo)
- Mark Zupan as Station Officer Steele (cameo)
- John Waters as Rosa (cameo)
- and more
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