- Johnny Knoxville as Jerry
- Bam Margera as Jerry
- Steve-O as Nibbles
- Wee-Man as Devil
- Preston Lacy as Brown Cat
- Chris Pontius as Tyke
- Ryan Dunn as Spike
- Dave England as Clint
- Brandon Novak as Uncle Pecos (cameo)
- Kat Von D as Jerry's Girlfriend (cameo)
- Rip Taylor as The Lion (cameo)
- Mark Zupan as Topo (cameo)
- John Waters as Canery (cameo)
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