- Johnny Knoxville as Top Cat
- Bam Mergera as Brain
- Ryan Dunn as Big Gus
- Chris Pontius as Griswald
- Steve-O as Fancy-Fancy
- Dave England as Pierre
- Preston Lacy as Officer Dibble
- Wee-Man as Spook
- Brandon Novak as Choo Choo (cameo)
- Kat Von D as Trixie (cameo)
- Mark Zupan as Lou Stickland (cameo)
- and more
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