- Benjamin "Ben" Fiedler as Ash Ketchum
- Joanne Fiedler as May
- Adam Fiedler as Professor Oak
- Arnie Stein as Pikachu
- Raylene Stein as Misty
- Zachary "Zach" Stein as Buizel
- Karen Sussman as Dawn
- Ashley Grunwald as Jessie
- Casey Nudelman as Nurse Joy
- Irwin Fiedler as Sparky
- Sandy Frost / Sacred Father as Iris
- DJ Quik as James
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