- Dr. Clinkscales as Calvin
- Little Bill as Hobbes
- April as Calvin's Mom
- Dorado as Calvin's Dad
- Isabel as Susie
- Kiku as Calvin's Teacher
- Garfield (from Garfield & Friends) as Calvin's Principal
- Shenzi (from The Lion King) as Rosalyn
- Bobby as Charlie
- Andrew as Calvin's Dummy
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