• Josephine "Jo" March as Miss Piggy
  • Friedrich Bhaer as Kermit the Frog
  • Margaret "Meg" March as Annie Sue Pig
  • Amy March as Janice
  • Elizabeth "Beth" March as Wanda
  • Theodore "Laurie" Laurence as Gonzo the Great
  • John Brooke as Dr. Bunsen Honeydew
  • Mr. Laurence as Floyd Pepper
  • Aunt March as Miss Mousey
  • Mr. March as Sam the Eagle

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